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Because triple-receptor agonists have shown notably larger effect sizes on systemic weight and metabolic markers than earlier single-target compounds, GLP-3 RT is increasingly the reference compound in research comparing multi-pathway versus single-pathway interventions

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It was observed that diabetic patients, regardless of the type of antidiabetic therapy, developed PD more than 6 years later than non-diabetic subjects or those who developed diabetes after the onset of PD

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