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This trial actually had many fewer dropouts in the study and overall reviewers have felt that the FAST trial is a more solid base than the CARES trial on which to base decisions about the use of febuxostat

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2.4.8 Furan-2-carbonyl Chloride (14) SOCl 2 (5.26 ml, 44.6 mmol) was added dropwise to a suspension of the furan-2-carboxylic acid ( 13 , 500 mg, 4.46 mmol) in toluene (22 ml)