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In conclusion, a better understanding of the mechanisms of nucleotide methylation in the pathogenesis of MAFLD will lead to better diagnostic, prognostic, and therapeutic interventions, and promise great advances in personalized medicine
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On the other hand, DFO improves blue light-triggered lipid peroxidation and cell death in ARPE-19 cells via reducing intracellular Fe 2+ level, ROS burst and lipid peroxidation accumulation in the model of blue light-induced retinal damage and degeneration ( 2+ levels, total iron levels, and lactate dehydrogenase (LDH) levels ( 3.1.2 Deferiprone Deferiprone (DFP) is a Food and Drug Administration (FDA) approved oral active iron chelator with brain permeability, cell permeability and skin permeability, which is currently used in the clinical treatment of iron overload
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