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GPX4-knockout mice exhibit cognitive decline and neurodegeneration associated with increased lipid peroxidation and ERK1/2 activation—not calpain 1 (CAPN1)—indicating ferroptosis, not apoptosis, as the driver (Hambright et al., 2017)
Reduced glutathione complex
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Differences in outcomes reported by patients with inflammatory bowel diseases vs their health care professionals
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