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Xanthohumol, a prenylated chalcone, regulates lipid metabolism by modulating the LXRα/RXR-ANGPTL3-LPL axis in hepatic cell lines and high-fat diet-fed zebrafish models
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In contrast, mutations in the PKC phosphorylation sites in the C-tail gave rise to “PKC-site mutants,” which demonstrated partial impairment in sequestration and endocytosis but completely diminished downregulation, indicating an important role for PKC in this process (Prinster, 2003)
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