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PET imaging of markers prevalent in innate immune cells has emerged as a powerful neuroinflammation imaging tool in MS research

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261 Mechanistically, GLP-1 signaling attenuates adipose inflammation—reducing macrophage infiltration and proinflammatory cytokines (IL-6, IL-1β, TNF-α)—while shifting adipokine tone toward a less protumorigenic milieu and depleting visceral/ectopic fat stores