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By blocking NNMT, 5 Amino 1mq can stimulate the increase of nicotinamide adenine dinucleotide (NAD+), and nicotinamide adenine dinucleotide (NAD+) is the core cofactor of cell metabolism, thus increasing metabolic rate and activating a gene named sirtuin-1 (SIRT1)

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10.1038/nbt.3440 39 DevinskyO.VezzaniA.O'BrienT

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