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I suspect, honestly, it's going to be higher because in the MSIDS model, in the 16 point model, where we have six major rivers of inflammation, infections, toxins, microbiome issues in the gut, leaky gut, intestinal hyperpilmeability with mast cell activation, vitamin mineral deficiencies, sleep disorders, those are the six big major rivers of inflammation causing an ocean of inflammation

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On the contrary, when the PARG activity was blocked by PDD00017273, protein PARylation levels were further increased (Figure 2B)