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On each dosing day, participants received a single oral dose of either 8 g of BNT–C060 (equivalent to 400 mg of curcumin extract) or 8 g of free curcumin (equivalent to 2,000 mg of curcumin extract) under fasting conditions with 300 mL of mineral water

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Moreover, Seahorse assay for bioenergetics performed on CD8 + T cells isolated from lymph nodes of CT26-tumour-bearing mice treated with DHB showed that DHB treatment decreased the extracellular acidification rate (ECAR) of CD8 + T cells (including basal ECAR, glycolytic capacity and glycolytic reserve) in vivo (Fig