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GNPs are also being functionalized using both peptides and oligonucleotides for perinuclear localization for various functions such as cell imaging, target- specific internalization, etc
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175 More recently, in 2015, an open-label clinical trial on 50 Parkinson’s disease patients showed that intramuscular injections of 100 mg of thiamine twice weekly led to significant and lasting improvements on a standardized Parkinson’s disease rating scale
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