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Data sources: English language literature was searched using various databases, such as PubMed, ScienceDirect, EBOSCOhost, Scopus, Web of Science, and Cochrane Library

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Besides, 8-hydroxydeoxyguanosine (8OHdG) is considered to be an important sensitive oxidative biomarker for evaluating oxidative sperm DNA damage, and its levels were found be significantly higher in infertile patients compared with normal ones [18, 44]