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Instead, he consistently incorporated squalane as a penetration-enhancing carrier, and his usage protocols specifically recommended applying squalane oil over a copper peptide serum to increase efficacy and help the peptide absorb into the skin

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This allows the thiolate anion to access the hydrophobic binding site exposed to the membrane, thereby aiding in the reduction of membrane-bound phospholipid hydroperoxides and the conjugation of additional hydrophobic electrophiles