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Figure 5 5.1 Experimental models and translational gaps Although significant mechanistic progress has been made using preclinical models, translating laboratory findings into effective clinical therapies for TBI remains a major challenge (Huang et al., 2023)
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While only subgroups of MDD patients regularly exhibit high baseline concentrations of cortisol, this paradigm did return DEGs in our patient cohort that have previously been associated with unipolar depression and other mood disorders