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Exposure of HDFs to lower doses of H 2 O 2 (100 μ M) for 72 hours induced premature senescence, as evidenced by enlarged and flattened cell morphology with a decreased nucleus-to-cytoplasm ratio, and most of the cells were stained blue for SA- β -gal, the typical characteristics of senescent cells

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Additional context on related cosmetic-research questions is available in GHK-Cu Benefits