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This 28-day window is particularly relevant when working with longer research protocols for example, studies involving Retatrutide, Semaglutide, or Tesamorelin, where consistent reagent quality across repeated sessions directly affects data integrity

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[1] [5] While GLP-1 receptors have variable distribution in reproductive tissues, the metabolic changes induced by GLP-1 agonists can have downstream effects on the hypothalamic-pituitary-ovarian axis, which governs menstrual function