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These findings indicate that a significant Th17/Treg imbalance occurs in AR

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Nonetheless, several microbiota-derived precursor molecules, such as tryptophan and its metabolite 5-hydroxytryptophan (5-HTP), which are precursors to serotonin, as well as tyrosine and levodopa (L-DOPA), which are precursors to dopamine, can cross the BBB and subsequently modulate CNS neurotransmitter availability [187]