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ROS stimulates the MAPK signal pathway, which is responsible for AP-1 formation (57)

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For macrophage polarization experiments, cells were then treated with either human recombinant IL-4 (10 ng/mL, Cedarlane Labs, Burlington, ON) or IFN-γ (10 ng/mL, eBioscience, San Diego, CA) for 48 h

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