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Currently, two CD38 antibody therapies are approved for the treatment of MM 1 : Daratumumab – approved as part of a combination regimen in newly diagnosed MM and as a sole agent in relapsed/refractory (RRMM) Isatuximab – approved as part of a combination regimen in newly diagnosed MM and as part of a combination regimen in RRMM Daratumumab and isatuximab both have proven efficacy in clinical trials and real-world treatment, confirming immunotherapy with CD38 antibodies as an effective approach for patients with MM either as a single agent or in combination with standard of care
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