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SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites

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No hGH Receptor Binding or IGF-1 Stimulation AOD9604 did not induce hyperglycaemia or reduce insulin secretion — in sharp contrast to chronic intact hGH treatment — and confirmed that the concept of hGH behaving as a pro-hormone is valid, with fragments capable of acting via mechanisms novel to traditional GH receptor-stimulated pathways