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Patients with B-ALL who met National Cancer Institute (NCI) standard-risk criteria at initial diagnosis fared better after relapse than did NCI high-risk patients.[15] Response to reinduction therapy Patients with marrow relapses who have persistent morphological disease at the end of the first month of reinduction therapy have an extremely poor prognosis, even if they subsequently achieve a second complete remission (CR).[24][Level of evidence B4]

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Your doctor may either assure you that your B₁₂ level is fine (so no B₁₂ needed), or they will arrange B₁₂ shots in tandem if necessary