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Although a large number of patients treated with methylphenidate have some positive therapeutic response, clinicians continue to struggle with selecting the appropriate formulation and optimal dose of methylphenidate to prescribe to a patient due to the high variability in therapeutic response

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Pathway analysis of siGSTO1 Bru-Seq data was also performed using IPA (Ingenuity Systems, Inc., Redwood City, CA) with genes showing fold change ≥2