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Among other things, ISCs are essential to energy metabolism in the electron transport chain (ETC)
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Thus, unlike angiogenic peptides [65,66,67,68,69,70,71,72,73], it is evident that BPC 157 angiogenesis [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40] does not align with Folkman’s first essential angiogenesis rule [76]