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355,356 In addition, apigenin administration downregulated NF-κB transcription activity, inhibitor of NF-κB (IκB)-α phosphorylation, transcription of p65 and p50 to nucleus, and inhibitor of κB kinase (IKK)-β expression in pancreatic cancer cells and xenograft mouse model

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Finally, we highlight directions for future research to target L-serine as a promising therapy