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Several suggest benefits, and the cardiac work in particular reported improved function and structure in a heart failure model (the Pharmacological Research paper reporting that NNMT inhibition improved cardiac function and structure in a heart failure model)
Safe & Effective Pet B12 Therapy
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The NHS symptoms list groups them into general anaemia symptoms (tiredness, breathlessness, headaches, loss of appetite, weight loss) and neurological signs (peripheral neuropathy, balance problems, depression, memory and concentration changes, sometimes mood changes or psychosis in advanced cases)